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HGF/c-Met signaling pathways are uncontrolled in human cancer via overexpression of HGF or c-Met, gene amplification, mutational activation of c-Met, down-regulation of Met-targeted miRNA, binding to other ligands, autocrine signaling, or abnormally high HGF levels

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[6] The researchers suggested that Ipamorelin might potentially influence osteoblasts (the cells responsible for bone formation) through mechanisms mediated by growth hormone, which might enhance their proliferation, growth, and specialization