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Autophagy and mitophagy as early barriers to tumor initiation and genomic instability In early tumorigenesis, autophagy functions predominantly as a tumor-suppressive mechanism by removing damaged organelles, misfolded proteins, and oncogenic substrates such as p62, thereby preventing genomic instability and malignant transformation

Some clinics use an intranasal formulation

Metabolomic analysis of follicular fluid from clinical PCOS patients revealed mitochondrial dysfunction, oxidationreduction potential imbalance, and increased oxidative stress in cumulus cells (122)