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A smaller subset of patients (roughly 58%) continues to experience occasional loose stools even after dose escalation, but these cases usually stabilize with additional weeks of treatment

10.1124/jpet.111.181529 [DOI] [PubMed] [Google Scholar] 88.Ponirakis G, Abdul-Ghani MA, Jayyousi A, Zirie MA, Qazi M, Almuhannadi H, Petropoulos IN, Khan A, Gad H, Migahid O, Megahed A, Al-Mohannadi S, AlMarri F, Al-Khayat F, Mahfoud Z, Al Hamad H, Ramadan M, DeFronzo R, Malik RA (2021) Painful diabetic neuropathy is associated with increased nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control

Conditional knockout of TGF-RII/Smad2 signals protects against acute renal injury by alleviating cell necroptosis, apoptosis and inflammation

Diabetes mellitus refers to metabolic diseases which are characterized by hyperglycemia that develops as a result of impairment in insulin secretion, insulin action, or both [5, 6]