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Key findings at the highest dose (12mg weekly): Up to 24% mean body weight reduction over 48 weeks Significant reductions in fasting glucose and insulin resistance markers Meaningful reductions in liver fat content, relevant for participants with metabolic-associated fatty liver disease Once-weekly subcutaneous dosing was generally well-tolerated For context, semaglutide at its approved dose achieves approximately 1517% body weight reduction over 68 weeks

[2] Fasting glucose: Measures current blood sugar levels to assess glucose tolerance

The official starting dose won't be confirmed until approval, but 2mg is most likely based on trial data, as it balances effectiveness with tolerability

Reviews are limited to testimonials on their website, which are consistently positive but unverified by a third party