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Similarly, in another research, a polysaccharide-enriched fraction obtained from CM also produced hypoglycemic effects in STZ-induced rats (Zhang et al., 2006).The anti-diabetic effects of C

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PAGln induces hypercontractility and altered Ca 2+ handling in cardiomyocytes The above physiological responses suggest that despite the lack of cardiac dysfunction as measured by echocardiography, there is a central effect of PAGln on the ability of the myocardium to contract and relax properly, manifesting as an elevation in LVEDP despite no change in afterload

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