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Despite promising Phase 2 results and an excellent safety profile, the compound could not demonstrate sufficient efficacy in the larger confirmatory trial to justify the investment required for continued pharmaceutical development toward regulatory approval

Each mL of sterile aqueous solution contains: Cyanocobalamin (B12)..........1000 mcg With sodium chloride 0.22% w/v, ammonium sulfate 0.1% w/v, citric acid 0.01% w/v, sodium citrate 0.008% w/v, and benzyl alcohol 1.0% v/v (preservative)

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Skin thickness increased by 70% after 12 days in one study