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Stable heavy isotopes such as hydrogen are used for labeling for quantitation in pharmacokinetic and metabolic application as tracers

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Standard / Gradual Approach The Symlin label steps the dose up only after nausea resolves at least three days between increases starting at 15 mcg per meal in type 1 diabetes and titrating in 15 mcg increments toward 3060 mcg, or starting at 60 mcg and moving to 120 mcg in type 2 diabetes [1]

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