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Although accumulating studies report the occurrence of hypoglycemia following the use of GLP-1RAs in patients with type 2 diabetes, most evidence comes from clinical trials (18,19), which is insufficient to systematically understand the risk or characteristics of such a relatively rare adverse event

Repeated minor strain is thought to be the major precipitating factor in tendinopathy, although further work is required to determine whether it is mechanical overstimulation or understimulation that leads to the change in tenocyte activity