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Beyond glycemia, GLP-1RAs also have beneficial effects on CV outcomes, and produce weight loss in a safe manner

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Usage: Semaglutide must be reconstituted with Bacteriostatic Water (BAC water) before use

NICE guidance (TA664) recommends Saxenda as a treatment option for weight management in adults within specialist weight management services (Tier 3 or 4) who have: A BMI of at least 35 kg/m (or at least 32.5 kg/m in people from certain minority ethnic groups) A BMI of at least 30 kg/m (or at least 27.5 kg/m in people from certain minority ethnic groups) and weight-related comorbidities Treatment should be discontinued if patients do not lose at least 5% of their initial body weight after 12 weeks at the maintenance dose of 3.0 mg