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Retatrutide has produced notable average weight loss in phase 2 research, yet it still needs larger studies, longer follow-up, and regulatory review before any standard dosing approach can be defined for routine care

Tirzepatide for 12 to 18 months at $179 per month totals roughly $2,150 to $3,200

2 Large randomised controlled trials such as the Diabetes Prevention Program and the Finnish Diabetes Prevention Study showed that lifestyle changes reduced the risk of developing diabetes by 58% at three-year follow up and by 27 to 38% after a mean follow up of 13 to 15 years