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5ad) and had no acute or chronic effect on mitochondrial functions in differentiated BAT primary cells, including mitochondrial respiration, proton production rate, proton leak respiration, coupling efficiency, maximal substrate oxidation, cellular respiration, non-mitochondrial and mitochondrial respiration, ATP-linked respiration, glycolysis, glycolytic proton production rate and glycolytic and oxidative phosphorylation-linked ATP production (Extended Data Fig

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It is plausible to postulate that the first and second GSH molecule should interact during the reductive half-reaction of the dithiol mechanism with the 1st and 2nd glutathione-interaction site, respectively

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