FIGURE 1 FIGURE 2 Glutathione is synthesized in the cytosol of all cells from their precursor amino acids: glutamic acid, cysteine and glycine by consecutive action of two enzymes: -glutamyl-cysteine (-GluCys) synthetase (also known as glutamate cysteine ligase, GCL) that in a first step uses glutamate and cysteine as a substrate to form the dipeptide -glutamyl-cysteine
It is commonly explored for its potential role in supporting skin appearance, collagen-related pathways, antioxidant activity, and overall skin wellness
References Gwyer D, Wragg NM, Wilson SL
demonstrated that oxidative stress, mediated by ROS, plays a crucial role in depression induction, and Nrf2 activation can mitigate oxidative stress by simultaneously regulating multiple potential mechanisms, including autophagy and ferroptosis (ZUO et al., 2022)