Paradoxically, the VD catabolic pathway mediated by CYP24A1a mitochondrial enzyme responsible for 24-hydroxylation of both 25(OH)D and 1,25(OH)2Dappears to be synergistically up-regulated by classical EIASMs [152]
Iron-rich dietary sources: Haem iron (better absorbed, 1535% absorption rate) is found in: Red meat (beef, lamb, pork) Poultry (chicken, turkey) Fish and seafood (particularly sardines, mackerel, and shellfish) Liver and organ meats (though pregnant women should avoid liver due to high vitamin A content) Non-haem iron (lower absorption, 220%) is present in: Dark green leafy vegetables (spinach, kale, broccoli) Pulses and legumes (lentils, chickpeas, beans) Fortified breakfast cereals and bread Dried fruits (apricots, figs, prunes) Nuts and seeds Enhancing iron absorption : Vitamin C significantly increases non-haem iron absorption
Patients should ask about the recommended approach for their specific situation, which may include: Following a liquid-only diet for 24 hours before the procedure (in addition to the standard bowel preparation) Whether any medication adjustment is recommended based on individual risk factors What additional precautions the anesthesia team might take Diabetes management considerations are important for patients using GLP-1 agonists for glycemic control
In addition, it is remarkable that the genes required for self-protection against the noxious effects of DTG and/or gliotoxin (i.e., gliA , gliT , and gtmA ) (Dolan et al., 2015) are strongly induced under zinc starvation (Vicentefranqueira et al., 2018)
