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Specifically, we applied genetic proxies for l-carnitine to genome-wide association studies (GWAS) of CVD and its risk factors (type 2 diabetes, glucose, HbA1c, insulin, low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol, triglycerides, apolipoprotein B, and blood pressure)

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The EMA European Public Assessment Reports (EPARs) for Wegovy, Ozempic, and Mounjaro provide further detail on the GI safety profiles of these approved agents and represent the most authoritative class-level evidence currently available