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Obstet Gynecol Adv

The prominent lymphocytic inflammationat least in the earlier relapsing phase of the diseaseis traditionally thought to be the primary insult with immune cells recruited into the CNS to induce recurrent chronic injury (Box 1)

Across oncology, cardiometabolic disease, liver and rare disorders, several late-stage readouts stood out not because they met endpoints, but because they reset expectations introducing new standards of care, validating new platforms, or delivering benefits where progress had stalled for decades

Loss of bone volume can be assessed using three-dimensional isoform display (54)