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This could help answering whether glutamate in the GLAST KO model was indeed the rate-limiting substrate from GSH synthesis or if neurodegeneration was mainly due to glutamate neurotoxicity
In terms of timing (McGee 2000): Primordial follicle to Primary follicle: unknown Primary follicle to Secondary follicle: at least 120 days Secondary follicle to Antral follicle: 71 days Antral follicle to Dominant follicle (ovulates): 14 days 120+71+14 =205 days + however long it took for the primordial follicle to make the primary follicle
doi: 10.1080/21505594.2019.1596506 197 RoedeB
Everson designs the combined protocol as one clinical picture
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