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Ozempic (semaglutide) is FDA-approved for type 2 diabetes management

Pharmaceuticals 16, 72

Gastrointestinal side effects represent one of the most common challenges when starting GLP-1 receptor agonist therapy, with diarrhea occurring in approximately one-quarter of patients during initial dose escalation

Summary Keywords amodiaquine, quinoneimine, cytotoxicity, endoplasmic reticulum stress, human glutathione S -transferases P1 Citation Zhang Y, den Braver-Sewradj SP, den Braver MW, Hiemstra S, Vermeulen NPE, van de Water B, Commandeur JNM and Vos JC (2018) Glutathione S -Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells