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Furthermore, inhibiting the mitochondrial permeability transition pore (mPTP), a key mediator of mitochondrial-driven cell death, with compounds like DBP-iPT has shown promise in protecting against cisplatin-induced ototoxicity by preserving mitochondrial membrane potential and dynamics (Kim Y

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Furthermore, both saturated and trans fats are linked to a decrease in the prevalence of beneficial microbial groups such as Bacteroidetes, Prevotella , Lactobacillus spp., and Bifidobacterium spp., while promoting a relative increase in Firmicutes (92, 93)

Os pesquisadores tambm pontuaram que a principal razo da deficincia de glutationa em adultos mais velhos pode ser a sntese diminuda devido menor disponibilidade de glicina e cistena