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Regarding their metabolic effects, the combination of a GLP-1RA and a SGLT2i significantly reduces HbA1c level, body weight, and SBP, with an additive effect on weight loss and SBP but not on HbA1c [35, 57,58,59]

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PlexusDx also recommends Microdose GLP-1 Protocol ($129/mo flat) for patients seeking gentler metabolic transition or combining medications via GLP-Squared Injection ($289/mo) to balance efficacy with tolerability