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Our guide to tirzepatide with methylcobalamin covers this distinction in depth, and our cyanocobalamin tirzepatide guide covers the more common formulation

5.0 [35]) and the 1.1 kDa reference peptide (IEP 5.0 [36]) showed high solubility whereas both larger polypeptides (14.4 kDa polypeptide, IEP 11.0 [37] and 66.4 kDa polypeptide, IEP 5.0 [38]) showed low solubility

The caution seems wise

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