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Combination therapy with anti-PD-L1 and compound 968 results in increased secretion of granzyme B, CXCL10, and CXCL11 by CD4 + and CD8 + T cells, thereby bolstering CD3 + T cell infiltration into tumor microenvironments [202]

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The inclusion criteria stipulated that participants be healthy male and female non-smokers, aged 30-79 years, who had not taken antioxidant supplements for at least one month prior to enrollment