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Any doctor administering this treatment off-label is obligated under SMC Ethical Code and Ethical Guidelines to ensure the patient has received a full and transparent account of these risks prior to consent

Reviewing previous IBD treatment response: If a biologic or advanced IBD treatment has not worked as expected, it may be appropriate to review treatment history, disease activity, drug levels, antibodies, timing of response and whether symptoms are due to inflammation or an overlapping condition

doi: 10.1111/j.1750-3639.1996.tb00854.x 147 Rodriguez MuruaSFarezMFQuintanaFJ

14 H 22 CuN 6 O 4 GHK-Cu Mechanism of Action Chelates Cu in a square-pyramidal coordination geometry, with labile axial positions available for ternary-complex formation