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Myth: Shaking the vial helps the powder dissolve faster and better

Nausea, vomiting, diarrhoea, constipation, and abdominal pain affect a significant proportion of patients, particularly during dose escalation

Uma Devi et al

M1-like macrophages amplify ferroptotic pressure through ferritinophagy-mediated release of labile Fe + , increased transferrin receptor (TfR1) expression, and restricted ferroportin activity, thereby enriching the tumor microenvironment (TME) with redox-active iron (71)