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Dosage should be split into two times a day, at least 3-4 hours apart

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These gender-specific effects may be important for the side effects of ibuprofen (such as increased risk of stroke) and more research is needed to investigate this possibility

The variations in catalytic activity between different polymorphic isoforms could be attributed to the relative distance between oxidized cysteine of Prdx VI and the activated GSH bound to the GSTP1-1 molecule [51]