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Avoid freezing, repeated warming, or leaving the vial at room temperature for long periods, as these can reduce peptide stability

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Formulations of cyanocobalamin injection containing benzyl alcohol as a preservative should also be avoided in premature neonates and those with hypersensitivity due to its association with gasping syndrome.[15][16][20] Monitoring: A history of the patients allergies/hypersensitivity should be obtained before administering cyanocobalamin injection

doi: 10.3945/ajcn.110.003483