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For instance, these measures include payment schemes, commercialization awards, patent purchases, and publicprivate partnerships in which public funding helps R&D at different development stages in pharmaceutical and biotech companies [61]
Upon activation, calcineurin dephosphorylates and stimulates TFEB, which in turn translocates into the nucleus where it binds to the coordinated lysosomal expression and regulation (CLEAR) sequence to upregulate expression of several genes involved in the autophagic pathway (Tong and Song, 2015
Despite interest in LCs metabolic role, little is known about how dosing strategyparticularly split versus single-dose intakemight influence performance outcomes
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