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Exposure assessment Periconceptional GLP-1 RA exposure was defined as liraglutide (ATC: A10BJ02) or semaglutide (ATC: A10BJ06) prescription redemption within 8 weeks from the date of the last menstruation, calculated using the date of birth and gestational age of the child recorded in the medical birth registry (Supplementary Fig

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In addition to L cells, preproglucagon neurons in the brain stem produce GLP-1, but how inflammation affects these neurons, and the role of brain-derived GLP-1 in local or systemic inflammation, are unknown