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Here, we benchmarked several engineered laccase templates 22,23,24,25 , identified an ancestral fungal variant with slight activity in HEK293T cells and performed extensive directed evolution on the yeast surface to improve its activity (Fig

In this context, discontinuing after the recovery period is appropriate

Because Wegovy can come with side effects, such as nausea or vomiting, patients are often first prescribed a lower dose that is gradually increased over several weeks