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joint involvement with pain/swelling/erythema), in the context of the patients history, with supporting evidence of elevated serum urate levels at a time other than during an acute attack Elevated serum urate levels alone are not diagnostic of gout, but may inform lifestyle changes (if relevant) and subsequent follow-up testing Treat gout flares with a NSAID, prednisone or low-dose colchicine

Together, they create a synergistic biological response that optimizes healing from all angles

doi: 10.1186/s13075-017-1353-6 101 Armas-GonzlezEDomnguez-LuisMJDaz-MartnAArce-FrancoMCastro-HernndezJDanelonGet al

Degraded tirzepatide delivers less of all three