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Description

The following data are based on findings in studies performed with sitagliptin or metformin individually

2.8% for 16 months, and 1.4% for 18 months

Cardiovascular outcome trials have demonstrated significant reductions in major adverse cardiovascular events with certain agents in this class (liraglutide, injectable semaglutide, and dulaglutide), leading to expanded indications for cardiovascular risk reduction

The MHRA is the medicines regulator for the whole of the United Kingdom, including Northern Ireland, following the implementation of the Windsor Framework for medicines (from 1 January 2025)