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Damiani, R

Studies suggest that AOD9604 does not bind the growth hormone receptor and does not activate the JAK2/STAT5 pathway, which accounts for the absence of growth-promoting or IGF-1-elevating effects observed in animal studies

Some evidence suggests that iron overload may also affect skeletal muscle metabolism, and reduced heme synthesis, along with dysregulated iron uptake or output, may contribute to abnormal glucose metabolism in aging muscle (Milford et al., 2019)