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The name is a nod to the Marvel characters rapid self-healing a piece of pop-culture branding, not a scientific claim

p27 negatively regulates cell cycle progression by inhibiting the Cyclin-dependent kinase 2 (CDK2)/Cyclin E complex, thereby blocking the G1-to-S phase transition (206)

Phase 2 combination trials reported 35-40% discontinuation rates due to GI side effects when both agents were dosed simultaneously

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