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A 2011 study published in Journal of Physiology and Pharmacology found BPC-157 significantly accelerated Achilles tendon healing in rats, with treated animals showing improved biomechanical properties and faster recovery of tendon strength compared to controls

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Non-genomic pathways enhance its protective role: Vit D has shown to stabilize mitochondrial function, relieve oxidative stress by activating the Nrf2 pathway, and modulate synaptic plasticity through stimulation of neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) 28