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GLP-1RA reduces steatosis and improves mitochondrial function and survival of primary human hepatocytes in vitro by reducing apoptosis and fatty acid-induced endoplasmic reticulum (ER) stress, and inducing autophagy of free fatty acids (FFAs) in treated cells ( PPAR , ACSL1, ApoB , and SHP1 (48, 49)

(Epub 2016 Jan 19)

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression

Zip8 KO mice exhibited impaired intestinal Mn uptake and systemic Mn deficiency, supporting its role in transcellular Mn uptake from the lumen into enterocytes ( While more is known about the transporters that handle Mn uptake into enterocytes, less is understood about which transporter exports Mn from enterocytes into the bloodstream on the basolateral membrane