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Cyclization: 1) preparation of cyclization reagent: dissolving iodine per gram in 30-40mL ethanol 2) Preparation of Vc reagent: dissolving Vc per gram in 20-30mL of purified water 3) Cyclization: the linear crude peptide was dissolved in 20% acetonitrile aqueous solution (1g of crude linear peptide in 100mL of 50% acetonitrile aqueous solution), and the linear peptide was dissolved and diluted to 1g/L with purified water

Int J Pharm Bio-Med Sci 1(09):192196 Dwivedi S, Dwivedi S, Patel P (2006) Medicinal plants used by the tribal and rural people of Satna district, Madhya Pradesh for the treatment of gastrointestinal diseases and disorders

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