Similarly, ABL kinase inhibitors such as imatinib protect oocytes by blocking c-Ablmediated phosphorylation of the pro-apoptotic factor TAp63, a pivotal executioner of DNA-damage-induced oocyte death
Among those team members were co-first authors Shanshan Liu, a postdoc in the lab who has long researched mitochondrial metabolism, and Mark Gad, a Ph.D student jointly supervised by Birsoy and Richard Hite, of Memorial Sloan Kettering Cancer Center
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Studies on methylene chloride-induced fatty liver