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Administration of CB-1158 (a small molecule inhibitor of arginase) can slow tumor growth rates, block myeloid cell-mediated suppression of T-cell proliferation, and increase the number of tumor-infiltrating CD8 + T cells and NK cells in mouse models of multiple tumors

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Scand J Gastroenterol 32:473477 Perry T (2002) Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4

188 Lesinurad (RDEA594) Lesinurad is a common URAT1 inhibitor that influences the serum uric acid concentration through the inhibition of URAT1 and OAT4