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Although HT is closely related to intestinal dysbiosis, because of the numerous types and individual differences of intestinal microflora, it is necessary to deeply understand the structure and mechanism of intestinal microflora to provide more possibilities for accurate medical treatment of HT

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Acknowledgements The principal author is thankful to the Chhatrapati Shahu Maharaj Research, Training and Human Development Institute (SARTHI), Pune, India, for financial support through the Chief Minister Special Research Fellowship-2019 (CMSRF-2019)