dulaglutide vs semaglutide vs tirzepatide GI risks similar between dulaglutide, and Comparative Gastrointestinal Safety of Dulaglutide,

A large retrospective study found a two-fold increased risk of anxiety and suicidal behavior and a three-fold increased risk of major depression among GLP-1RA users

Patients using semaglutide have reported not only improvements in their physical health but also enhancements in their overall well-being and quality of life

We searched PubMed and Embase databases using the terms glucagon-like peptide receptor agonists

After the matching, there were 1022 matched pairs of GLP-1RA and insulin users with no significant between-group difference in the baseline characteristics except for age, hyperlipidemia, and neuropathy (Additional file 1: Table S3)