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Key benefits for perimenopausal women: Supports tendon, ligament, and joint tissue repair at a time when estrogen loss reduces collagen synthesis and increases injury vulnerability May improve gut lining integrity, which can become compromised during perimenopause due to hormonal and microbiome shifts Promotes exercise recovery through angiogenesis and growth hormone receptor upregulation demonstrated preclinically in animal models, with potential relevance to maintaining lean muscle mass Administration method: Subcutaneous injection near the target tissue is the most studied delivery method

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Many patients notice reduced appetite and gradual weight loss within the first few weeks

doi: 10.1016/S0140-6736(19)31149-3 7 SohnMDietrichJWNauckMALimS