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Samples were loaded into standard Monolith capillaries and measured using the Monolith 2020 pico-RED instrument (NanoTemper) at 100% excitation and medium microscale thermophoresis power at 25 C

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Endothelial dysfunction, which refers to an imbalance between various factors involved in relaxation and contraction, coagulation and anticoagulation, as well as inflammation and anti-inflammation, may play a substantial role in the pathogenesis of atherosclerosis and cardiovascular disease (94)