The mechanism has been associated with enhanced blood flow to active musculature, however, it might be more far-reaching as either ammonia homeostasis could be improved, or ATP production could be increased via greater availability of malate
Theoretically, yes
Oral Sprays: A quick spray inside your cheek works in a similar way to sublingual drops, using the blood supply in the mouth for fast absorption
Acknowledgements The authors research is funded by Instituto de Salud Carlos III (ISCIII)-Fondo de Investigacion Sanitaria (FIS)-Fondo Europeo de Desarrollo Regional FEDER (grants PI18/01366, PI21/00251, PI19/00588, P21/01453, PI18/01133, PI19/00815, PI22/00469, PI22/00050), European Research Area PerMed JTC2018 (KIDNEY ATTACK AC18/00064) and the RICORS programme to RICORS2040 (RD21/0005/0001), and also by Comunidad de Madrid en Biomedicina (grant P2022/BMD-7223, CIFRA_COR-CM)