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Additionally, while our Co-IP assay demonstrated a physical interaction between SIRT5 and TFR1, the use of a more spatially sensitive technique, such as Proximity Ligation Assay (PLA), would provide stronger in situ evidence for their direct interaction

Morning administration may be preferable for patients who experience nausea, as they can manage symptoms during waking hours when they can employ coping strategies such as eating small, low-fat meals, staying hydrated, or using anti-nausea medications if prescribed

The peptide is designed exclusively for in vitro experiments , such as: receptorligand binding studies, enzyme activity assays, cell proliferation and signaling tests, epitope mapping, and other laboratory applications

Statistical analysis All data were presented as mean standard deviation