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The small amount of NO synthesized may further react with ROS to form peroxynitrite

World J Biol Psychiatry (2006) 7(3):1317

While injections are known for their effectiveness, they also come with potential downsides: Pain at the injection site, especially for those new to self-injections Requires strict hygiene practices to avoid infections Sharp peaks and gradual declines can cause mood swings or irritability Higher testosterone levels can sometimes convert to estrogen, potentially requiring additional medication Possible skin reactions at the injection site Despite these drawbacks, many find the consistent release of testosterone worth the occasional discomfort