10.1016/j.jnutbio.2013.06.005 J
Recommended Safe Dosage While there is no universal standard dose, typical safe dosage ranges in the industry vary by application: Health Supplements: Most oral formulations range from 250 mg to 1,000 mg per day
You can try to reduce this side effect by eating healthy foods that wont irritate your digestive tract, such as bananas, potatoes, or oatmeal
The treatment normalized serum corticosterone levels, enhanced central GABA and serotonin concentrations and reduced peripheral inflammation and gut microbiota profiling revealed a reduction in potentially pathogenic genera ( Acinetobacter, Enterococcus, Bacillus ) and increased abundance of beneficial taxa ( Muribaculum, Alistipes, Lactobacillus ), indicating the therapeutic potential of targeted psychobiotic intervention for stress-related disorders (Tyagi et al., 2025)