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The nature of how impaired glutamate cysteine ligase, the enzyme that naturally produces Glyteine, can make cells more susceptible to mutagens due to lower glutathione [4, 5] has been well studied

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This randomized, double-blind, placebo-controlled trial in 58 older adults identified as "pre-frail" found an decrease in a Frailty Index score and an improvement in the hand grip test in individuals supplemented with L-carnitine (1.5 g/day) over 10 weeks but not in those given a placebo (118)