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Storage & Handling Use appropriate laboratory safety protocols Keep containers sealed when not in use Store under controlled environmental conditions Frequently Asked Questions: What is Hospira Water intended for

doi: 10.3389/fphar.2026.1844144 Received 31 March 2026 Revised 26 June 2026 Accepted 29 June 2026 Published 27 July 2026 Volume 17 - 2026 Edited by Qingbin Cui, University of Toledo College of Medicine and Life Sciences, United States Reviewed by Kaushik Neogi, Deemed to be University, India Long Wu, Wuhan University, China Updates Copyright 2026 Lofaro, Ferri, Mazzilli, Bonacorsi, Simonini and Boraldi

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The HNMT enzyme, which clears intracellular histamine, depends on SAMe, a molecule produced through the methylation pathway