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In Phase 3 trials, oral orforglipron 36 mg daily produced mean weight loss of approximately 14.7% at 72 weeks comparable to injectable semaglutide 2.4 mg

Finally, carnitine is also used to reduce the toxicity of compounds deriving from partially metabolized acyl groups and breakdown of xenobiotics by facilitating their excretion in carnitine ester form (Figure 1)