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Exercise plus the GLP-1 RA worked best.[ref] Works even at lower doses: A 2025 study found that people who werent as consistent in taking daily doses or in taking the prescribed amount still had significant weight loss.[ref] Dietary recommendations for reducing nausea: Dietary recommendations for reducing nausea include avoiding fatty foods, eating well-cooked vegetables instead of raw ones, and including complex carbohydrates

Many users find that injecting in the evening minimizes daytime nausea since the worst side effects occur in the first 12 to 24 hours after injection

2 Around the same time, scientists determined the sequences of the human glucagon and GLP-1 proteins