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The LCLT group images showed significant lesion improvement from day 7 to 14 compared with those of the placebo group

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Similar findings were observed in an ischemia/reperfusion rat forebrain injury, in which chronic trimetazidine (alone or with progesterone) alleviated SOD and glutathione decrease while preventing malondialdehyde and lipid peroxidase increase [181]

As humans do not produce TMCA, we examined the levels of non-12-OH FXR-antagonistic BA species in humans, and found that the levels of non-12-OH FXR-antagonistic BAs (HDCA and UDCA-related species) were positively correlated with T3 levels in euthyroid human study participants (Fig